Buy CJC-1295 DAC Peptide Italy
CJC-1295 DAC (Drug Affinity Complex) is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the anterior pituitary gland to release growth hormone (GH).
Its prolonged half-life allows for sustained increases in serum growth hormone levels, resulting in elevated insulin-like growth factor 1 (IGF-1) concentrations.
This peptide shows promise in treating growth hormone deficiencies and potential applications in anti-aging therapies, making it significant in modern medical research.
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HGH Fragment CJC-1295 Dac Pre Mixed 2.5mg
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HGH Fragment & CJC-1295 Dac 2.5mg
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CJC-1295 DAC
£24.20 – £97.46 This product has multiple variants. The options may be chosen on the product page
CJC-1295 DAC Mechanism Of Action
CJC-1295 DAC is a modified version of growth hormone-releasing hormone (GHRH) composed of 30 amino acids. It functions by binding to specific receptors in the anterior pituitary gland, stimulating the release of growth hormone. This binding triggers the pulsatile release of growth hormone (GH), closely mimicking the body’s natural secretion patterns.
The addition of a drug affinity complex (DAC) notably extends the peptide’s half-life, allowing for sustained GH release over extended periods.
Upon administration, CJC-1295 DAC induces a temporary state that enhances GH release, characterized by increased serum GH levels and changes in the serum protein profile, including fluctuations in serum albumin concentrations. Importantly, this mechanism leverages the peptide’s ability to stimulate endogenous GH secretion rather than depending on exogenous GH administration.
The formulation’s stability and efficacy are further augmented by the inclusion of lysine and maleimidoproprionic acid (MPA), enhancing CJC-1295 DAC’s therapeutic potential. Italy Research indicates that GH levels in healthy adult subjects increase similarly to those observed in clinical contexts, showcasing its promise as a therapeutic agent for metabolic and anti-aging applications.
Additionally, findings suggest that both the dosage and frequency of injections significantly influence the GH secretion profile, warranting further investigation into optimal treatment strategies for various therapeutic purposes.
Structure of CJC-1295 DAC
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol
PubChem CID: 56841945
What Are The Research Benefits of CJC-1295 DAC
Enhanced Growth Hormone Secretion: Promotes increased endogenous secretion of growth hormone, mimicking natural pulsatile release patterns. This function plays a vital role in the increase of muscle mass and strength, potentially aiding in the increase of lean muscle mass and improving physical performance.
Prolonged Action: The extended half-life allows for less frequent injections, which can enhance patient adherence to treatment protocols. Italy Research indicates that, with the Drug Affinity Complex (DAC), CJC-1295 possesses a longer half-life than other peptides, resulting in sustained effects in the body.
Optimised Treatment Protocols: The flexibility in dosage and administration frequency supports tailored therapeutic approaches, catering to individual patient needs.
Promotion of Protein Synthesis: Evidence suggests that CJC-1295 DAC can effectively promote protein synthesis, a crucial process for muscle growth and recovery.
Metabolic Support: This peptide may assist in fat reduction and promote a leaner body composition while enhancing muscle mass. Italy Studies indicate that CJC-1295 DAC aids in lipolysis, the process through which the body breaks down fats for energy.
Increased Bone Density: Growth hormone significantly contributes to bone health, and CJC-1295 DAC may stimulate its production, potentially increasing bone density and reducing the risk of fractures and osteoporosis.
Improved Serum Protein Profile: Alters serum albumin concentrations, which contributes positively to overall metabolic health.
Enhanced Skin Health: Italy Scientific studies suggest that by stimulating growth hormone production, CJC-1295 DAC may promote healthier skin, aiding in cell regeneration and repair, and increased collagen production, leading to improved skin elasticity and reduced wrinkles [4].
Improved Sleep: As an analogue of growth hormone-releasing hormone (GHRH), Italy research has suggested that CJC-1295 DAC may enhance sleep patterns by affecting the sleep-wake cycle.
Cognitive Enhancement: Emerging research suggests that CJC-1295 DAC may have positive effects on cognitive function, potentially enhancing memory, focus, and overall mental clarity by promoting growth hormone levels that support neuronal health and regeneration.
Anti-Aging Properties: The peptide may provide potential benefits in mitigating the signs of aging through improved body composition and increased vitality.
Reduced Side Effects: In comparison to exogenous GH administration, CJC-1295 DAC may exhibit fewer adverse effects, such as transient hypotension or injection site reactions.
Therapeutic Agent: It holds possible applications in managing various metabolic disorders, including obesity and sarcopenia, demonstrating its versatility in treatment strategies.
Buy CJC-1295 DAC peptide vial available in 2mg, 5mg, and 10mg glass vials for research purposes online from Direct Peptides Italy today!
CJC-1295 DAC Pre-Mixed Pen
The CJC-1295 DAC pre-mixed peptide pen is a user-friendly delivery system that simplifies the administration of this long-acting growth hormone-releasing peptide. With a 2mg pre-mixed solution, it eliminates the need for reconstitution and ensures accurate dosing, making it ideal for researchers.
This innovative tool enhances treatment adherence and maximizes the peptide’s efficacy in studies related to metabolic health, anti-aging, and muscle growth.
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GHRP-6 and CJC-1295 DAC Blend Nasal Spray
The GHRP-6 and CJC-1295 DAC nasal spray marks a significant advancement in peptide delivery for growth hormone research. GHRP-6 stimulates growth hormone release, while CJC-1295 DAC prolongs its effect.
This nasal spray allows for rapid absorption, increased bioavailability, and precise dosing without injections, enhancing convenience and compliance. It has the potential to expand research on muscle hypertrophy, metabolic function, and growth hormone dynamics, offering a valuable tool for peptide therapy studies.
Buy CJC-1295 DAC and GHRP-6 Nasal Spray available in 15ml and 30ml spray bottles.
Frequently Asked Questions (FAQs) about CJC-1295 DAC
Is CJC-1295 DAC the same as CJC-1295?
CJC-1295 DAC (Drug Affinity Complex) is a modified form of the peptide CJC-1295. The key difference between the two is that CJC-1295 DAC has a drug affinity complex added to it, which prolongs its half-life in the body compared to the original CJC-1295 (Mod GRF 1-29). This modified form of GHRH allows for a more sustained release of growth hormone, making CJC-1295 DAC potentially more suitable for certain therapeutic uses or specific research goals.
However, many scientists believe that the shorter half-life of CJC-1295 without DAC (Mod GRF 1-29) is more natural, as it stimulates a short pulse of Human Growth Hormone.
What is the half-life of CJC-1295 DAC?
Understanding the pharmacokinetics of CJC-1295 DAC and its non-DAC version is crucial for optimizing growth hormone stimulation. CJC-1295 DAC has an extended half-life of 5 to 8 days, allowing for less frequent dosing and better patient adherence.
In contrast, CJC-1295 without DAC has a much shorter half-life of 30 minutes to 2 hours, requiring more frequent injections and potentially leading to unstable hormone levels. Researchers should consider these differences when designing clinical protocols to enhance the effectiveness of growth hormone therapies.
Is CJC-1295 DAC legal?
The legality of CJC-1295 DAC varies globally, with many countries, including the US, classifying it as a research chemical for laboratory purposes and not approved for human use. It is intended for scientific research, and buyers must comply with local laws and regulations before purchasing or using it.
Can CJC-1295 DAC be combined with other peptides?
Yes, CJC-1295 DAC can effectively combine with other peptides to enhance therapeutic outcomes.
One notable pairing is with GHRP-6, a growth hormone-releasing peptide that works synergistically with CJC-1295 DAC to boost growth hormone release. This combination can lead to increased lean muscle mass, improved fat metabolism, and better overall recovery.
Additionally, pairing CJC-1295 DAC with HGH Fragment 176-191, known for its fat-burning effects, may provide benefits of muscle preservation while promoting fat loss.
Does CJC-1295 DAC Peptides have any side effects?
Clinical observations indicate that local adverse reactions at the injection site are common, with itching, irritation, and erythema frequently reported. Additionally, instances of transient hypotension have been recorded post-administration.
Systemically, users may experience gastrointestinal disturbances, including nausea and abdominal pain, with some reporting episodes of diarrhoea.
Notably, fluctuations in cortisol levels and shifts in the serum protein profile merit attention in research contexts. Given these considerations, it is imperative for researchers and clinicians supervising the administration of CJC-1295 DAC to maintain vigilant monitoring of these side effects and to adhere to established clinical guidelines to ensure optimal outcomes for patients involved in clinical trials or therapeutic use.
Where is the best place to buy CJC-1295 DAC peptides?
It is important to buy CJC-1295 DAC peptides from reputable suppliers like Direct Peptides Italy to ensure the quality and integrity of the peptides for research studies.
Buy CJC-1295 DAC Nasal Spray available in 15ml and 30ml spray bottles online from Direct Peptides Italy.
Summary of Research Applications
- Increases the half-life, allowing for less frequent dosing
- Increase of growth hormone secretion and IGF-1 without negatively impacting the plasticity of growth hormone release
- Increases muscle mass and enhances physical strength
- Aids in weight management and fat loss
- Enhances quality of sleep and promotes restful nights
- Boosts cognitive capabilities and mental alertness
- Supports the maintenance of a healthy skeletal structure
- Elevates mood and increases overall energy levels
- Enhances libido and boosts sexual performance
- Promotes tissue repair and regeneration
- Strengthens the immune system response
- Contributes to improved fertility in women
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CJC-1295 DAC Peptide Quality Assured
At Direct Peptides, quality assurance is vital to our commitment to advancing peptide therapy research. We conduct rigorous analytical testing at every production stage to ensure our CJC-1295 DAC peptides meet the highest purity and potency standards.
Each batch undergoes thorough evaluations, including high-performance liquid chromatography (HPLC) and mass spectrometry, to confirm its identity and concentration.
Our strict quality control protocols guarantee a purity level over 99%, instilling confidence in researchers who rely on our products. By prioritizing quality assurance, we aim to provide reliable compounds that support groundbreaking scientific exploration.
References For Further Reading
[1] A. Volpe, G. Coukos, A. Barreca, G. Giordano, P. G. Artini, A. R. Genazzani (1991) Clinical use of growth hormone-releasing factor for induction of superovulation – Human Reproduction, Volume 6, Issue 9, 1 October 1991, Pages 1228–1232.
[2] S L Teichman, A Neale, B Lawrence, C Gagnon, J-P Castaigne, L A Frohman (2006) Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults – Journal of Clinical Endocrinology and Metabolism, 2006 Mar, Volume 91 (Issue 3), Pages 799-805.
[3] M Ionescu and L A. Frohman (2006) Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog – The Journal of Clinical Endocrinology & Metabolism, Volume 91, Issue 12, 1 December 2006, Pages 4792–4797.
[4] L Sackmann-Sala, J Ding, L A Frohman, J J Kopchick (2009) Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects – Growth Hormone and IGF Research, 2009 Dec, Volume 19 (Issue 6), Pages 471-7.
[5] M Alba, D Fintini, A Sagazio, B Lawrence, JP Castaigne, L A Frohman, R Salvatori (2006) Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse – American Journal of Physiology. Endocrinology and Metabolism, 2006 Dec, Volume 291 (Issue 6), Pages E1290-4.
[6] M C van Hout and E Hearne (2016) Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions – Substance Use & Misuse, Volume 51, 2016 – Issue 1, Pages 73-84.
Why Choose Direct Peptides Italy?
Buy CJC-1295 DAC with 99% purity from Direct Peptides Italy, your leading provider of CJC-1295 peptides. What sets us apart is our exclusive selection of peptide formulations. Our range includes peptide vials in 2mg, 5mg, and 10mg, innovative peptide blends designed for potential synergistic effects, convenient peptide nasal sprays in 15ml and 30ml bottles, and ready-to-use pre-mixed peptide pens. At Direct Peptides Italy, we cater to the diverse needs of researchers, ensuring access to the exact formulation needed for their specific projects.
ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.
DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Italy Direct Peptides website: https://italy.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.
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