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Highest Quality | For Research Use Only

IGF-1 LR3

Buy IGF-1 LR3 Peptide Italy

IGF-1 LR3, or Insulin-like Growth Factor-1 Long R3, is a synthetic analog of the naturally occurring peptide hormone, IGF-1. It is engineered with an altered amino acid sequence, which includes an extended chain of 13 amino acids at the N-terminus and replacement of the Arg (R) for the Glu(E) at position three. These modifications enhance its biological activity by reducing binding to IGF-binding proteins (IGFBPs) and extending its half-life.

Italy Research suggests IGF-1 LR3 plays a crucial role in muscle development and repair. By mimicking the action of insulin, it stimulates the uptake of nutrients into muscle cells and promotes protein synthesis, resulting in increased muscle mass and strength. Its longer half-life allows it to act over a more extended period, amplifying its effects on muscle growth.

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Potential Benefits of IGF-1 LR3 Peptide

  • Promotes Muscle Growth and Performance Enhancement: IGF-1 LR3, a potent variant of the Insulin-Like Growth Factor, is known to stimulate muscle growth and improve performance in athletes. By binding to and activating the IGF-1 receptor, it promotes protein synthesis and cell proliferation, contributing to muscle hypertrophy [1].
  • Accelerates Fat Loss: Studies have suggested that IGF-1 LR3 can help burn fat and increase energy levels. This makes it an effective alternative to other growth hormones for individuals aiming for weight loss or body recomposition [2].
  • Implications for Tendon Healing: While there are mixed results, some research suggests that the LR3 variant of IGF-1, which binds with low affinity to circulating binding proteins, may have potential implications for tendon healing strategies [3].
  • Improved Insulin Sensitivity: Research suggests by using IGF-1 LR3, there might be benefits like less insulin use, fewer insulin sensitivity issues, and improved overall recovery [4].
  • Stimulation of Bone Formation: Researchers believe that IGF-1 LR3 stimulates bone formation, potentially having a direct effect on osteoblasts [5].
  • Cardiomyopathy Prevention in Type 1 Diabetes: According to research, IGF-1 LR3 (Long R3) has been found to regulate oxidative stress and DNMT-SOCS1/3-IGF-1 signaling, providing valuable insight into its potential impact on cardiomyopathy prevention in individuals with type 1 diabetes. [6].

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4665094/

[2] https://pubmed.ncbi.nlm.nih.gov/15240644/

[3] https://www.mdpi.com/ 1422-0067/24/3/2370

[4] https://pubmed.ncbi.nlm.nih.gov/10905488/

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5966339/

[6] https://pubmed.ncbi.nlm.nih.gov/34163008/

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Direct Peptides website: https://italy.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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