Rigin (Topical)

Description

Rigin 50mg (Topical Peptide)

This product is intended for research purposes only. To be used by trained professionals only.

Rigin, also known as Palmitoyl Tetrapeptide7, is a short synthetic peptide made up of the amino acids: palmitoyl, glycine, glutamine, and arginine It has the analogue of the natural occurring matrikine peptide, which is thought to play an important role in controlling the ECM turnover (extracellular matrix) and cellular activity.

According to an early clinical study, Rigin topical peptide stimulates the combination of ECM elements such as collagen and elastin while blocking the generation of pro-inflammatory cytokines. It may also influence gene expression in ECM remodelling, cell proliferation, and inflammation [1].

Studies have revealed that Rigin topical peptide or Palmitoyl Tetrapeptide 7 has the ability to modulate the skin’s inflammatory response, a key factor in its effectiveness in skincare. Studies have documented that this peptide can diminish interleukin production by as much as 40%, demonstrating its significant anti-inflammatory properties. Interleukins are cytokines that play a pivotal role in inflammation, and their overproduction can lead to skin aging and damage. By curbing their production, Rigin topical peptide not only soothes inflammation but also sets the stage for skin repair and rejuvenation [1].

Furthermore, Rigin’s efficacy extends to the modulation of gene expression crucial for the extracellular matrix’s (ECM) remodelling and inflammation management. This dual-action mechanism underscores the peptide’s holistic approach to skincare, influencing both the structural integrity and inflammatory pathways of the skin. The ECM, a network of proteins including collagen and elastin, provides structural support to the skin. By promoting ECM remodelling, Rigin topical peptide helps in maintaining the skin’s firmness and elasticity, thereby counter acting the signs of aging [2].

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References:

[1] Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications. J Cosmet Dermatol. 2015 Jun;14(2):152-60. by Mondon P, Hillion M, Peschard O, Andre N, Marchand T et al.

[2] The extracellular matrix: Structure, composition, age-related differences, tools for analysis and applications for tissue engineering. J Tissue Eng. 2014 Dec by Kular JK, Basu S, Sharma RI.

Molecular Formula: C34H62N8O7

Molecular Weight: 694.9 g/mol

ALL CONTENT AND PRODUCT INFORMATION AVAILABLE ON THIS WEBSITE IS FOR EDUCATIONAL PURPOSES ONLY.

DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Italy Direct Peptides website: https://italy.direct-peptides.com is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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